top of page

PUBLICATIONS

 

FULL PAPERS

 

  1. Barison GAS, D’Amora P, Izidoro MA, Corinti M, Martins LM, Bonduki CE, Castro RdeA, Girão MJBC, Gomes MTV. Metabolomic Profiling of Peripheral Plasma by GC-MS and Correlation With Size of Uterine Leiomyomas, Journal of the Endocrine Society 2022 May; 6(7):1-14, https://doi.org/10.1210/jendso/bvac061.

Link: https://academic.oup.com/jes/article/6/7/bvac061/6568527?searchresult=1

 

 

  1. D'Amora P, Silva IDCG, Budib MA, Ayache R, Silva RMS, Silva FC, Appel RM, Júnior SS, Pontes HBD, Alvarenga AC, Arima EC, Martins WG, Silva NLF, Diaz RS, Salzgeber MB, Palma AM, Evans SS, Nagourney RA. Towards risk stratification and prediction of disease severity and mortality in COVID-19: Next generation metabolomics for the measurement of host response to COVID-19 infection. PLoS One. 2021 Dec 1;16(12):e0259909. doi: 10.1371/journal.pone.0259909. PMID: 34851990; PMCID: PMC8635335.

 

Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0259909

 

 

  1. D'Amora P, Silva IDCG, Tewari KS, Bristow RE, Cappuccini F, Evans SS, Salzgeber MB, Addis-Bernard PJ, Palma AM, Marchioni DML, Carioca AAF, Penner KR, Alldredge J, Longoria T, Nagourney RA. Platinum resistance in gynecologic malignancies: Response, disease free and overall survival are predicted by biochemical signature: A metabolomic analysis. Gynecol Oncol. 2021 Aug 23:S0090-8258(21)00646-6. doi: 10.1016/j.ygyno.2021.08.001. Epub ahead of print. PMID: 34446269.

 

Link: https://www.gynecologiconcology-online.net/article/S0090-8258(21)00646-6/fulltext

 

 

  1. da Silva IDCG, de Castro Levatti EV, Pedroso AP, Marchioni DML, Carioca AAF, Colleoni GWB. Biochemical phenotyping of multiple myeloma patients at diagnosis reveals a disorder of mitochondrial complexes I and II and a Hartnup-like disturbance as underlying conditions, also influencing different stages of the disease. Sci Rep. 2020 Dec 14;10(1):21836. doi: 10.1038/s41598-020-75862-4.

 

Link: https://www.nature.com/articles/s41598-020-75862-4

 

 

  1. Carioca AAF, Steluti J, Carvalho AM, Silva AM, Silva IDCGD, Fisberg RM, Marchioni DM. Plasma metabolomics are associated with metabolic syndrome: A targeted approach. Nutrition. 2020 Nov 20;83:111082. doi: 10.1016/j.nut.2020.111082.

 

Link: https://www.sciencedirect.com/science/article/abs/pii/S0899900720303658?via%3Dihub

 

  

  1. da Silva I, da Costa Vieira R, Stella C, Loturco E, Carvalho AL, Veo C, Neto C, Silva SM, D'Amora P, Salzgeber M, Matos D, Silva CR, Oliveira JR, Rabelo I, Yamakawa P, Maciel R, Biscolla R, Chiamolera M, Fraietta R, Reis F, Mori M, Marchioni D, Carioca A, Maciel G, Tomioka R, Baracat E, Silva C, Granato C, Diaz R, Scarpellini B, Egle D, Fiegl H, Himmel I, Troi C, Nagourney R. Inborn-like errors of metabolism are determinants of breast cancer risk, clinical response and survival: a study of human biochemical individuality. Oncotarget. 2018 Aug 3;9(60):31664-31681. doi: 10.18632/oncotarget.25839.

 

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114970/

 

 

  1. Okada LSDRR, Oliveira CP, Stefano JT, Nogueira MA, Silva IDCGD, Cordeiro FB, Alves VAF, Torrinhas RS, Carrilho FJ, Puri P, Waitzberg DL. Omega-3 PUFA modulate lipogenesis, ER stress, and mitochondrial dysfunction markers in NASH - Proteomic and lipidomic insight. Clin Nutr. 2018 Oct;37(5):1474-1484. doi: 10.1016/j.clnu.2017.08.031.

 

Link: https://www.clinicalnutritionjournal.com/article/S0261-5614(17)30314-X/fulltext

 

 

  1. Serafim PVP, Figueiredo AG Jr, Felipe AV, Turco EGL, Silva IDCGD, Forones NM. Study of lipid biomarkers of patients with polyps and colorectal cancer. Arq Gastroenterol. 2019 Oct-Dec;56(4):399-404. doi: 10.1590/S0004-2803.201900000-80.

 

Link: https://www.scielo.br/j/ag/a/RFHySs6K468TVJzC9xSb38N/?lang=en

 

 

  1. Santos JR, Waitzberg DL, da Silva IDCG, Junior TCT, Barros LRC, Canuto GAB, Faccio AT, Yamaguchi LF, Kato MJ, Tavares MFM, Martinez AC, Logullo AF, Torrinhas RSMM, Ravacci G. Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study. Oncotarget. 2020 May 5;11(18):1637-1652. doi: 10.18632/oncotarget.27575.

 

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210010/

 

 

  1. Oliveira EML, Montani DA, Oliveira-Silva D, Rodrigues-Oliveira AF, Matas SLA, Fernandes GBP, Silva IDCGD, Lo Turco EG. Multiple sclerosis has a distinct lipid signature in plasma and cerebrospinal fluid. Arq Neuropsiquiatr. 2019 Oct 24;77(10):696-704. doi: 10.1590/0004282X20190122.

 

Link: https://www.scielo.br/j/anp/a/mFrbFYRVHPHyXWBw6sy8rNz/?lang=en

 

 

  1. de Souza JS, Laureano-Melo R, Herai RH, da Conceição RR, Oliveira KC, da Silva IDCG, Dias-da-Silva MR, Romano RM, Romano MA, Maciel RMB, Chiamolera MI, Giannocco G. Maternal glyphosate-based herbicide exposure alters antioxidant-related genes in the brain and serum metabolites of male rat offspring. Neurotoxicology. 2019 Sep;74:121-131. doi: 10.1016/j.neuro.2019.06.004.

 

Link: https://www.sciencedirect.com/science/article/pii/S0161813X18305205?via%3Dihub

 

 

  1. Garla P, Sala P, Torrinhas RSM, Machado NM, Fonseca DC, da Silva MM, Ravacci GR, Belarmino G, Ishida RK, Guarda IFMS, de Moura EGH, Sakai P, Santo MA, da Silva IDCG, Pereira CCA, Heymsfield S, Corrêa-Giannella MLC, Calder PC, Waitzberg DL. Reduced intestinal FADS1 gene expression and plasma omega-3 fatty acids following Roux-en-Y gastric bypass. Clin Nutr. 2019 Jun;38(3):1280-1288. doi: 10.1016/j.clnu.2018.05.011.

 

Link: https://www.clinicalnutritionjournal.com/article/S0261-5614(18)30183-3/fulltext

 

 

  1. Bastos KLM, Quaio CR, Lima FR, Araújo IM, Araújo CAT, Piazzon FB, Silva IDCGD, Benevides GN, Tannuri AC, Tannuri U, Azevedo RA, Kim CA. Biochemical profile in an infant with neonatal hemochromatosis shows evidence of impairment of mitochondrial long-chain fatty acid oxidation. Clin Mol Hepatol. 2019 Mar;25(1):86-91. doi: 10.3350/cmh.2018.0005.

 

Link: https://www.e-cmh.org/journal/view.php?doi=10.3350/cmh.2018.0005

 

 

  1. Usón Junior PLS, Wagner J, Corpa MVN, Coelho IM, Nagourney RA, Yamaguchi NH. Metastatic carcinoma of unknown primary with complete metabolic response following sorafenib-based chemotherapy. SAGE Open Med Case Rep. 2019 Mar 21;7:2050313X19838739. doi: 10.1177/2050313X19838739.

 

Link: https://journals.sagepub.com/doi/10.1177/2050313X19838739?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&

 

 

  1. Laus AC, da Silva IDCG, Cordeiro FB, Lo Turco EG, de Souza Viana L, Carvalho AL. Is Lipidomic the Answer to the Search of a Biomarker for Organ Preservation Protocol in Head and Neck Squamous Cell Carcinoma? Pathol Oncol Res. 2018 Oct;24(4):931-935. doi: 10.1007/s12253-017-0336-x.

 

Link: http://por.hu/2018/24/4/0931/0931a.pdf

 

 

  1. de Figueiredo Junior AG, Serafim PVP, de Melo AA, Felipe AV, Lo Turco EG, da Silva IDCG, Forones NM. Analysis of the Lipid Profile in Patients with Colorectal Cancer in Advanced Stages. Asian Pac J Cancer Prev. 2018 May 26;19(5):1287-1293. doi: 10.22034/APJCP.2018.19.5.1287

 

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031810/

 

 

  1. Peixoto RD, Gomes LM, Sousa TT, Racy DJ, Shigenaga M, Nagourney RA. Efficacy of oral metformin in a patient with metastatic adrenocortical carcinoma: Examination of mechanisms and therapeutic implications. Rare Tumors. 2018 Jan 31;10:2036361317749645. doi: 10.1177/2036361317749645.

 

Link: https://journals.sagepub.com/doi/10.1177/2036361317749645?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

 

 

  1. Anzai Á, Marcondes RR, Gonçalves TH, Carvalho KC, Simões MJ, Garcia N, Soares JM Jr, Padmanabhan V, Baracat EC, da Silva IDCG, Maciel GAR. Impaired branched-chain amino acid metabolism may underlie the nonalcoholic fatty liver disease-like pathology of neonatal testosterone-treated female rats. Sci Rep. 2017 Oct 13;7(1):13167. doi: 10.1038/s41598-017-13451-8.

 

Link: https://www.nature.com/articles/s41598-017-13451-8

 

 

  1. Miranda AM, Carioca AAF, Steluti J, da Silva IDCG, Fisberg RM, Marchioni DM. The effect of coffee intake on lysophosphatidylcholines: A targeted metabolomic approach. Clin Nutr. 2017 Dec;36(6):1635-1641. doi: 10.1016/j.clnu.2016.10.012.

 

Link: https://www.clinicalnutritionjournal.com/article/S0261-5614(16)31287-0/fulltext

 

 

  1. Scarpellini B, Zanoni M, Sucupira MC, Truong HM, Janini LM, da Silva ID, Diaz RS. Correction: Plasma Metabolomics Biosignature According to HIV Stage of Infection, Pace of Disease Progression, Viremia Level and Immunological Response to Treatment. PLoS One. 2017 Feb 24;12(2):e0173164. doi: 10.1371/journal.pone.0173164. Erratum for: PLoS One. 2016 Dec 12;11(12):e0161920.

 

Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173164

 

 

  1. Sala P, Belarmino G, Machado NM, Cardinelli CS, Al Assal K, Silva MM, Fonseca DC, Ishida RK, Santo MA, de Moura EG, Sakai P, Guarda IF, da Silva ID, Rodrigues AS, Pereira CA, Heymsfield S, Doré J, Torrinhas RS, Giannella-Neto D, Waitzberg DL. The SURMetaGIT study: Design and rationale for a prospective pan-omics examination of the gastrointestinal response to Roux-en-Y gastric bypass surgery. J Int Med Res. 2016 Dec;44(6):1359-1375. doi: 10.1177/0300060516667862.

 

Link: https://journals.sagepub.com/doi/10.1177/0300060516667862?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

 

 

  1. Korkes HA, Sass N, Moron AF, Câmara NO, Bonetti T, Cerdeira AS, Da Silva ID, De Oliveira L. Lipidomic assessment of plasma and placenta of women with early-onset preeclampsia. PLoS One. 2014 Oct 17;9(10):e110747. doi: 10.1371/journal.pone.0110747.

 

Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110747

 

 

  1. Oliveira LD, Korkes H, Turco EL, Bertola R, Sass N, Bonetti T, Moron AF, Silva ID. PP098. Lipidic fingerprinting in women with early-onset preeclampsia: A first look. Pregnancy Hypertens. 2012 Jul;2(3):293. doi: 10.1016/j.preghy.2012.04.209.

 

Link: https://www.sciencedirect.com/science/article/abs/pii/S2210778912002383?via%3Dihub

 

 

 

 

RESEARCH ABSTRACTS

 

 

Brazilian Society of Clinical Oncology (SBOC)

 

 

19th Brazilian Congress of Clinical Oncology 2015

 

 

  1. D’Amora P, Silva IDCG, Salzgeber MB, Girão MJBC, Kleine JPFO, Forde G, Bristow R, DiSaia PJ, Evans S, Nagourney RA. A phase II study in epithelial ovarian cancer (EOC) to correlate drug sensitivity and metabolic signatures with objective response (OR), time to progression (TTP), and overall survival (OS). Annals of the Brazilian Congress of Clinical Oncology (SBOC), Foz do Iguaçú, Paraná, Brazil, 2015.

 

 

 

American Society of Clinical Oncology (ASCO)

 

 

2013 – ASCO Annual Meeting

 

  1. Colacino-Silva F, Maluf FC, Buzaid AC, Nagourney RA, Yamaguchi NH, D'Amora P, Evans S, Bernard PJ, Francisco F. International collaboration in personalized medicine for the treatment of advanced and drug-refractory cancers: Clinical application of human tumor primary culture analyses. J Clin Oncol 31, 2013 (suppl; abstr e13562). doi:10.1200/jco.2013.31.15_suppl.e13562.

 

 

2014 – ASCO Annual Meeting

 

  1. Nagourney RA, Gansl RC, Lopes G, Buzaid AC, Maluf FC, D'Amora P, Yamaguchi NH, Colacino-Silva F, Mello AN. Cost benefit analysis of laboratory directed chemotherapy for advanced pancreatic cancer in U.S. and Brazilian patients. J Clin Oncol 33, 2015 (suppl; abstr e17782).

 

 

2015 – ASCO Annual Meeting

 

 

  1. Nagourney RA, Bernard PJ, Francisco FR, Nagourney A, Evans S, Deo EA, D’Alpino RP. Metformin activity in advanced adrenocortical carcinoma: A comparative analysis in human tumors. J Clin Oncol 36, 2018 (suppl; abstr e14568). doi: 10.1200/JCO.2018.36.15_suppl.e14568.

 

 

2016 - American Association for Cancer Research (AACR). The Rivkin Center for Ovarian Cancer & the American Association for Cancer Research (AACR). 11th Biennial Ovarian Cancer Research Symposium – September 12-13, 2016. University of Washington, Seattle, Washington.

 

  1. D’Amora P, Silva IDCG, Salzgeber MB, Girão MJBC, Bristow RE, Evans SS, DiSaia PJ, Nagourney RA. Correlation between drug sensitivity and metabolic signatures with objective response (OR), time to progression (TTP), and overall survival (OS) in advanced epithelial ovarian cancer (EOC): a phase II study. Proceedings of 11th Biennial Ovarian Cancer Research Symposium, poster TME&E-021, page 138. Winner of AACR-Aflac, Inc. Scholar-In-Training Award.

 

 

2017 - AACR International Conference & the Latin American Cooperative Oncology Group (LACOG) – May 4-6, 2017, São Paulo, Brazil.

 

  1. D’Amora P, Silva IDCG, Salzgeber MB, Girão MJBC, Bristow RE, Evans SS, DiSaia PJ, Nagourney RA. Metabolic signatures in patients with advanced epithelial ovarian cancer: correlation with clinical response parameters in a phase II study. Proceedings of AACR & LACOG International Conference, poster session B, page 82. Winner of AACR-LACOG Scholar-In-Training Award.

 

2022 - AACR Annual Meeting – April 4-6, 2022, New Orleans, Louisiana.

  1. Complete remission in advanced epithelial ovarian cancer is predicted by metabolic signatures measured in the media of patient’s primary culture 3D tumor explants: A metabolomic analysis. Adam J. Nagourney, Paulo D'Amora, Ismael Dale Cotrim Guerreiro Silva, Steven S. Evans, Robert A. Nagourney. Nagourney Cancer Institute, Long Beach, CA, Federal University of São Paulo, São Paulo, Brazil, Rational Therapeutics, LLC, Long Beach, CA.

Link: https://www.abstractsonline.com/pp8/#!/10517/presentation/12833

 

2022 – ASCO Annual Meeting – June 3-7, 2022, Chicago, Illinois.

  1. Drugging the Undruggable-Targeting P53: A Comparative Analysis of APR-246 and COTI-2 in human tumor primary culture explants. Adam Jeremiah Nagourney, Steven Scott Evans, Max Serge Duesberg, Paulo D'Amora, Paula J. Bernard, Eric Francisco, Robert Alan Nagourney. J Clin Oncol 40, 2022 (suppl 16; abstr e15092). DOI: 10.1200/JCO.2022.40.16_suppl.e15092. Abstract #: e15092.

bottom of page